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Medical physics is a branch of applied physics concerning the application of physics to medicine. It generally concerns physics as applied to medical imaging and radiotherapy, although a medical physicist may also work in many other areas of healthcare. A medical physics department may be based in either a hospital or a university and its work is likely to include research, technical development and clinical healthcare.

Medical imaging


Treatment of disease


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Magnetic Resonance Materials in Physics, Biology and Medicine

Structural–acoustic modal analysis of cylindrical shells: application to MRI scanner systems
Mon, 26 Oct 2009 18:00:23 -0000
Abstract Object  The acoustic noise in a magnetic resonance imaging (MRI) scanner bore is mainly introduced by the vibration of gradient coils. The interaction between acoustic modes in the scanner bore and structure modes in the coil structure leads to structural–acoustic coupling. In order to implement quiet MRI design, the structural–acoustic coupling mechanism in MRI machines needs to be fully investigated. Materials and method  Structural analysis was first implemented using Love’s classical shell theory. The concept of a “virtually closed cavity” was used in the acoustic modal analysis of the gradient coil duct. The dispersion curves and the number of modes per frequency band were used to reveal modal distribution properties for both structural modes and acoustic modes. Structural–acoustic coupling modes were identified by superposition of the dispersion diagrams of the structural waves and acoustic waves. Experimental validation was implemented separately for the structural analysis and acoustic analysis. Results  Independent structural modes and acoustic modes and their distribution patterns were calculated up to 3000Hz with various boundary conditions. Coupling modes were clearly revealed using the analysis procedures presented in this paper and were found to be in agreement with the ones identified from experimental measurements. Conclusion  These methods are effective for coupled and uncoupled modal analysis of MRI scanner systems and can be used for quiet MRI design or sound absorber design for existing MRI systems. Content Type Journal ArticleCategory Research ArticleDOI 10.1007/s10334-009-0185-zAuthors Gemin Li, Queen’s University Department of Mechanical Engineering McLaughlin Hall Kingston ON K7L 3N6 CanadaChris K. Mechefske, Queen’s University Department of Mechanical Engineering McLaughlin Hall Kingston ON K7L 3N6 Canada Journal Magnetic Resonance Materials in Physics, Biology and MedicineOnline ISSN 1352-8661Print ISSN 0968-5243
Quantitative metabolic profiles of 2nd and 3rd trimester human amniotic fluid using 1H HR-MAS spectroscopy
Thu, 24 Sep 2009 16:42:27 -0000
Abstract Object  To establish and compare normative metabolite concentrations in 2nd and 3rd trimester human amniotic fluid samples in an effort to reveal metabolic biomarkers of fetal health and development. Materials and methods  Twenty-one metabolite concentrations were compared between 2nd (15–27 weeks gestation, N = 23) and 3rd (29–39 weeks gestation, N = 27) trimester amniotic fluid samples using 1H high resolution magic angle spinning (HR-MAS) spectroscopy. Data were acquired using the electronic reference to access in vivo concentrations method and quantified using a modified semi-parametric quantum estimation algorithm modified for high-resolution ex vivo data. Results  Sixteen of 21 metabolite concentrations differed significantly between 2nd and 3rd trimester groups. Betaine (0.00846±0.00206 mmol/kg vs. 0.0133±0.0058 mmol/kg, P < 0.002) and creatinine (0.0124±0.0058 mmol/kg vs. 0.247±0.011 mmol/kg, P < 0.001) concentrations increased significantly, while glucose (5.96±1.66 mmol/kg vs. 2.41±1.69 mmol/kg, P < 0.001), citrate (0.740±0.217 mmol/kg vs. 0.399±0.137 mmol/kg, P < 0.001), pyruvate (0.0659±0.0103 mmol/kg vs. 0.0299±0.286 mmol/kg, P < 0.001), and numerous amino acid (e.g. alanine, glutamate, isoleucine, leucine, lysine, and valine) concentrations decreased significantly with advancing gestation. A stepwise multiple linear regression model applied to 50 samples showed that gestational age can be accurately predicted using combinations of alanine, glucose and creatinine concentrations. Conclusion  These results provide key normative data for 2nd and 3rd trimester amniotic fluid metabolite concentrations and provide the foundation for future development of magnetic resonance spectroscopy (MRS) biomarkers to evaluate fetal health and development. Content Type Journal ArticleCategory Research ArticleDOI 10.1007/s10334-009-0184-0Authors Brad R. Cohn, University of California Department of Radiology & Biomedical Imaging 1600 Divisadero Street, Room C-250 Box 1667 San Francisco CA 94115 USABonnie N. Joe, University of California Department of Radiology & Biomedical Imaging 1600 Divisadero Street, Room C-250 Box 1667 San Francisco CA 94115 USAShoujun Zhao, University of California Department of Radiology & Biomedical Imaging 1600 Divisadero Street, Room C-250 Box 1667 San Francisco CA 94115 USAJohn Kornak, University of California Department of Radiology & Biomedical Imaging 1600 Divisadero Street, Room C-250 Box 1667 San Francisco CA 94115 USAVickie Y. Zhang, University of California Department of Radiology & Biomedical Imaging 1600 Divisadero Street, Room C-250 Box 1667 San Francisco CA 94115 USARahwa Iman, University of California Department of Radiology & Biomedical Imaging 1600 Divisadero Street, Room C-250 Box 1667 San Francisco CA 94115 USAJohn Kurhanewicz, University of California Department of Radiology & Biomedical Imaging 1600 Divisadero Street, Room C-250 Box 1667 San Francisco CA 94115 USAKiarash Vahidi, University of California Department of Radiology & Biomedical Imaging 1600 Divisadero Street, Room C-250 Box 1667 San Francisco CA 94115 USAJingwei Yu, University of California Department of Laboratory Medicine San Francisco CA USAAaron B. Caughey, University of California Department of Obstetrics & Gynecology San Francisco CA USAMark G. Swanson, University of California Department of Radiology & Biomedical Imaging 1600 Divisadero Street, Room C-250 Box 1667 San Francisco CA 94115 USA Journal Magnetic Resonance Materials in Physics, Biology and MedicineOnline ISSN 1352-8661Print ISSN 0968-5243
ESMRMB 2009 Congress, Antalya, Turkey, 1–3 October: Abstracts, Thursday
Thu, 24 Sep 2009 14:34:38 -0000
ESMRMB 2009 Congress, Antalya, Turkey, 1–3 October: Abstracts, Thursday Content Type Journal ArticleDOI 10.1007/s10334-009-0175-1 Journal Magnetic Resonance Materials in Physics, Biology and MedicineOnline ISSN 1352-8661Print ISSN 0968-5243 Journal Volume Volume 22 Journal Issue Volume 22, Supplement 1 / October, 2009
ESMRMB 2009 Congress, Antalya, Turkey, 1–3 October: Abstracts, Saturday
Thu, 24 Sep 2009 14:34:38 -0000
ESMRMB 2009 Congress, Antalya, Turkey, 1–3 October: Abstracts, Saturday Content Type Journal ArticleDOI 10.1007/s10334-009-0177-z Journal Magnetic Resonance Materials in Physics, Biology and MedicineOnline ISSN 1352-8661Print ISSN 0968-5243 Journal Volume Volume 22 Journal Issue Volume 22, Supplement 1 / October, 2009
ESMRMB 2009 Congress, Antalya, Turkey, 1–3 October: Abstracts, Friday
Thu, 24 Sep 2009 14:34:36 -0000
ESMRMB 2009 Congress, Antalya, Turkey, 1–3 October: Abstracts, Friday Content Type Journal ArticleDOI 10.1007/s10334-009-0176-0 Journal Magnetic Resonance Materials in Physics, Biology and MedicineOnline ISSN 1352-8661Print ISSN 0968-5243 Journal Volume Volume 22 Journal Issue Volume 22, Supplement 1 / October, 2009
ESMRMB 2009 Congress, Antalya, Turkey, 1–3 October: EPOStm Posters / Paper Posters / Info-RESO
Thu, 24 Sep 2009 14:34:35 -0000
ESMRMB 2009 Congress, Antalya, Turkey, 1–3 October: EPOStm Posters / Paper Posters / Info-RESO Content Type Journal ArticleDOI 10.1007/s10334-009-0178-y Journal Magnetic Resonance Materials in Physics, Biology and MedicineOnline ISSN 1352-8661Print ISSN 0968-5243 Journal Volume Volume 22 Journal Issue Volume 22, Supplement 1 / October, 2009

 
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