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Stereology is a spatial version of sampling theory. The word "stereology" was coined in May 1961 by the founding fathers of the International Society for Stereology to describe the set of methods that allow a 3-D interpretation of structures based on observations made on 2-D sections. Stereology is therefore often referred to as the science of estimating higher dimensional information from lower dimensional samples. For example, measurements of the area fraction of a certain grain type made on a planar section cut through an opaque petrological sample will reveal the actual 3-D grain volume fraction.
Classically, stereological techniques involved mathematical or computer modeling of the structures under investigation and applying statistical procedures. These methods (which usually assume randomness of the structure under investigation) are now referred to as "model based stereology". These methods are especially popular in materials science, metallurgy and petrology where shapes of e.g. crystals may be modelled.
Since the early 1970s a new branch of stereology have evolved, where the needed randomness is obtained by random spatial sampling. These methods are referred to as "design based stereology" and provide unbiased estimates depending on very few and weak assumptions about the investigated structure. These methods have gained increasing popularity in the biomedical sciences—especially in lung-, kidney-, bone-, cancer- and neuro-science—as these methods do not depend on an exact geometric model of the investigated structure. Many of these applications are directed toward determining the number of elements in a particular structure. The application of stereology is based upon determining the density of the object within the space of interest. The product of the density and the volume of the space within which the objects lie provides an estimate of object number. An experimental concern is that the distribution of objects within the space of interest may not be uniform. Thus, the sample, although random, may not yield a result that is representative of the true density.
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stereology (Stereology) Sat, 07 Nov 2009 16:53:21 -0000
Wer braucht schon einen iPod wenn er einen iAudio9 haben kann? Neue News!
RT @whits_twits RT @stereology Und noch eine neue Review auf stereology.de: Däscher Electro-Indie Rock gefäig?Dúän was füh!
Rock_RT (Markus Grampp) Fri, 06 Nov 2009 23:24:02 -0000
RT @whits_twits RT @stereology Und noch eine neue Review auf stereology.de: Däscher Electro-Indie Rock gefäig?Dúän was füh!
RT @stereology Und noch eine neue Review auf stereology.de: Däscher Electro-Indie Rock gefäig?Dúän was füh!
whits_twits (Whitney G) Fri, 06 Nov 2009 23:11:07 -0000
RT @stereology Und noch eine neue Review auf stereology.de: Däscher Electro-Indie Rock gefäig?Dúän was füh!
Absoluter Hattrick, 3 Reviews an einem Tag. Diesmal gehts mit The xx weiter. Das Album selbst heiÃt auch #xx und lädt zum Träumen ein :)
stereology (Stereology) Fri, 06 Nov 2009 21:32:34 -0000
Absoluter Hattrick, 3 Reviews an einem Tag. Diesmal gehts mit The xx weiter. Das Album selbst heißt auch #xx und lädt zum Träumen ein :)
RT @stereology Und noch eine neue Review auf stereology.de: Dänischer Electro-Indie Rock gefällig?Dúné wären was für dich!
Rock_RT (Markus Grampp) Fri, 06 Nov 2009 10:59:16 -0000
RT @stereology Und noch eine neue Review auf stereology.de: Dänischer Electro-Indie Rock gefällig?Dúné wären was für dich!
Und noch eine neue Review auf stereology.de: Dänischer Electro-Indie Rock gefällig?Dúné wären was für dich!
stereology (Stereology) Fri, 06 Nov 2009 10:52:49 -0000
Und noch eine neue Review auf stereology.de: Dänischer Electro-Indie Rock gefällig?Dúné wären was für dich!
Blue Histology - A Brief Introduction to Stereology - Introduction to the techniques most often used in stereology research. Straightforward descriptions and pictures illustrate the methods.
Easy Measure - Offers descriptions of the methods and mathematics used in stereology. Covers many techniques and offers a bulletin board for users to post questions.
International Society for Stereology - Inviting membership. Includes abstracts of journals, courses and details of related conferences.
PharmaNess.com - Help scientists and agencies in staining procedures for biological samples. Provide stereological and morphological quantitative analyses.
QuanToxPath - Consultants on stereology and 2D geometrical quantification in bio-medical research.
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Stereology for Precision Agriculture - The use of stereology in agriculture is explained. Seeing the proper implementation of procedures is important in understanding how to construct other experiments.
Stereology Resource Center - Aiming to provide biomedical and biosciences researchers with resources for unbiased stereological research, scientific measurement and analysis. Services include training, software, consulting, tissue sample analysis and testing, independent validation from Chester, Maryland.
Meta Description: [ The Stereology Resource Center providesresearchers with efficient, state-of-the-art, and affordable research methods and resources for unbiased stereological research and measurement. Our services include research program consulting, laboratory tissue analysis and sample testing, stereology work... ]
Systems Planning and Analysis, Inc. - Developer of Stereologer, an integrated software/hardware system for stereological analysis of biological structures.
Meta Description: [ The Sterologer System is tool for scientists and researchers who analyze biological tissues. It uses
unbiased sampling and geometric probes in conjunction with video microscopy systems to provide state of the art morphological analysis of tissue
samples. ]
Three-Dimensional Counting: An Accurate and Direct Method to Estimate Numbers of Cells in Sectioned Material - 1988 paper by Robert W. Williams and Pasko Rakic presenting the counting box method. Updated with authors' comments on their paper and on the Abercrombie's correction.
Meta Description: [ Neurogenetics at the University of Tennessee, Memphis. This server is the gateway to The Portable Dictionary of the Mouse Genome (over 20,000 gene loci), The Mouse Brain Library, databases on mouse brain size and structure, and online publications. ]
Visiopharm - Semi-automated stereology and advanced image analysis solutions for quantitative studies turning images into knowledge. Delivering software, hardware, training, and custom development.
Meta Description: [ Visiopharm contributes to the succesful development of new drugs, by realizing the full potential of quantitative image analysis in drug discovery and development projects. ]
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