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Clinical Chemistry current issue

[Editorials] CSF Serine Enantiomers and Glycine in the Study of Neurologic and Psychiatric Disorders
Hashimoto, K. Thu, 28 Aug 2008 00:00:00 -0000

[Editorials] Saliva Analysis for Monitoring Dialysis and Renal Function
Nagler, R. M. Thu, 28 Aug 2008 00:00:00 -0000

[Editorials] Coffee Consumption and Coronary Heart Disease: Paradoxical Effects on Biological Risk Factors versus Disease Incidence
van Dam, R. M. Thu, 28 Aug 2008 00:00:00 -0000

[Perspective] Evaluating New Diagnostic Technologies: Perspectives in the UK and US
Price, C. P., Christenson, R. H. Thu, 28 Aug 2008 00:00:00 -0000

[Mini-Review] Defining a Role for Novel Biomarkers in Acute Coronary Syndromes
Bonaca, M. P., Morrow, D. A. Thu, 28 Aug 2008 00:00:00 -0000
Background: Biomarkers play a pivotal role in the diagnosis and treatment of patients with cardiovascular disease. Active investigation has brought forward an increasingly large number of novel candidate markers; however, few of these markers have yet to be incorporated into routine clinical use. Content: This review discusses biomarkers currently used in the setting of acute coronary syndromes. In this context, we assess the contemporary unmet needs for novel biomarkers in acute ischemic heart disease and the related challenges faced in developing new biomarkers to the point of integration into clinical practice. In particular, we address the impact of the availability of increasingly sensitive biomarkers of myocardial necrosis on the potential roles for novel biomarkers of inflammation, thrombosis, and ischemia. Summary: Although active investigation has produced a growing list of candidate novel biomarkers for the care of patients with cardiovascular disease, it has become increasingly challenging to find appreciable incremental clinical benefit for their addition to existing markers, in particular newer, more analytically sensitive cardiac troponin assays. A major challenge for researchers and clinicians will be to demonstrate whether candidate novel markers are useful in improving diagnosis and guiding clinical treatment.
[Review] Key Issues in the Developing Synergism between Cardiovascular Imaging and Biomarkers
Jaffe, A. S. Thu, 28 Aug 2008 00:00:00 -0000
Background: Sophisticated methods of cardiac imaging have the potential to revolutionize the care of patients with cardiovascular disease. The benefits of these state-of-the art imaging techniques can be enhanced by their use in combination with new cardiac biomarkers. This review addresses potentially useful interactions between imaging and biomarkers. Content: Areas were defined in which the combined use of novel imaging techniques and biomarkers would be most beneficial. This review addresses multiple cardiovascular conditions for which the useful aspects of imaging and biomarkers are likely to be positively synergistic, including acute and chronic ischemic heart disease, heart failure, myocarditis, hypertension, and atherosclerosis. Conclusions: The synergistic use of imaging techniques and biomarkers will enhance the investigation of many key issues and questions and will be an important resource in the future.

 

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A new building for a new magnet - Adventures installing a 750 MHz system, in german.

A Teacher's Guide to Superconductivity for High School Students - Quite a bit of information here about super conductors and magnets.

Concepts Of Superconductors - Basics and very advanced theory of super conductors. .

404 Development of Superconductong Magnets - How the Japanese are building a 1 GHz magnet. The race is on.

404 Directory of Superconductor Resources on the Web. - Provides links to web resources on all aspects of superconductors, including research and development, applications, producers, education and public policy.

HFML, 20 tesla Bitter Magnet - Some diagrams and theory about Bitter magnets

Magnet cutaway - What happens when your magnet can't be resurrected after the last quench. Make it an educational tool.

Magnet theory and production - A really good manual about production and theory of magnets. In german.

Mikes Method for Magnet Shimming - A method for shimming a magnet written by Mike Abell in 1988. The methos still works these days, on more modern systems. After all shimming is shimming.

NMR Tips for Shimming, Part 1 - The first of a two part series of articles by Dr. W.E. Hull. about shimming, the tune alogrithim, sample preparation. Very informative and helpful article about shimming a NMR system.
Meta Description: [ Bruker BioSpin designs, manufactures and distributes enabling life science and analytical research tools based on magnetic resonance core technology. ]

NMR Tips for Shimming, Part 2 - The second of a two part series of articles by Dr. W.E. Hull. about shimming, the simplex alogrithim. Very informative and helpful article about shimming a NMR system.
Meta Description: [ Bruker BioSpin designs, manufactures and distributes enabling life science and analytical research tools based on magnetic resonance core technology. ]

Oxford 270 NMR Magnet Destruction - The inside of a superconducting magnet
Meta Description: [ JEOL--a world leader in electron microscopes (SEMs and TEMs), electron beam lithography, defect review and inspection tools) and analytical instruments including mass spectrometers, NMRs and ESRs. ]

SCM - A flash tutorial of the SCM keypad. Very useful if you still have one.

Shimit - Shimming software from ScienceSoft. Only for Varians.

Shimming Ain't Magic - The SAM Manual- The definitive shimming manual. Very useful for everyone.

500 Shimming an NMR Magnet - Gerry Pearson's old (1991) but very useful manual about shimming.

500 Stone Lab NMR Guide - Locking and Shimming. Tips and tricks. Useful information.

Superconducting Magnets. - Probably suitable for NMR.
Meta Description: [ Superconducting Magnets. ]

Superconducting Technology - A very interesting discussion of superconductors, cryogenics and magnets.

Superconductivity Basics - A very interesting set of pages on theory and practice.

Superconductors.org - Superconductor Information for the Beginner. A nicely written site, with much basic information. Great for students.

UofS Chemistry - Magnet Shimming. Part of a series of lectures about NMR. This part (5) presents a very useful discussion of the Science of shimming a NMR magnet. Equations of various RT shims are presented.