Manganese is a gray-white metal, resembling iron. It is a hard metal and is very brittle, fusible with difficulty, but easily oxidized. Manganese metal is ferromagnetic only after special treatment.
The most common oxidation states of manganese are +2, +3, +4, +6 and +7, though oxidation states from +1 to +7 are observed. Mn2+ often competes with Mg2+ in biological systems, and manganese compounds where manganese is in oxidation state +7 are powerful oxidizing agents.
[Mini-Review] Defining a Role for Novel Biomarkers in Acute Coronary Syndromes Bonaca, M. P., Morrow, D. A. Thu, 28 Aug 2008 00:00:00 -0000
Background: Biomarkers play a pivotal role in the diagnosis and treatment of patients with cardiovascular disease. Active investigation has brought forward an increasingly large number of novel candidate markers; however, few of these markers have yet to be incorporated into routine clinical use.
Content: This review discusses biomarkers currently used in the setting of acute coronary syndromes. In this context, we assess the contemporary unmet needs for novel biomarkers in acute ischemic heart disease and the related challenges faced in developing new biomarkers to the point of integration into clinical practice. In particular, we address the impact of the availability of increasingly sensitive biomarkers of myocardial necrosis on the potential roles for novel biomarkers of inflammation, thrombosis, and ischemia.
Summary: Although active investigation has produced a growing list of candidate novel biomarkers for the care of patients with cardiovascular disease, it has become increasingly challenging to find appreciable incremental clinical benefit for their addition to existing markers, in particular newer, more analytically sensitive cardiac troponin assays. A major challenge for researchers and clinicians will be to demonstrate whether candidate novel markers are useful in improving diagnosis and guiding clinical treatment.
[Review] Key Issues in the Developing Synergism between Cardiovascular Imaging and Biomarkers Jaffe, A. S. Thu, 28 Aug 2008 00:00:00 -0000
Background: Sophisticated methods of cardiac imaging have the potential to revolutionize the care of patients with cardiovascular disease. The benefits of these state-of-the art imaging techniques can be enhanced by their use in combination with new cardiac biomarkers. This review addresses potentially useful interactions between imaging and biomarkers.
Content: Areas were defined in which the combined use of novel imaging techniques and biomarkers would be most beneficial. This review addresses multiple cardiovascular conditions for which the useful aspects of imaging and biomarkers are likely to be positively synergistic, including acute and chronic ischemic heart disease, heart failure, myocarditis, hypertension, and atherosclerosis.
Conclusions: The synergistic use of imaging techniques and biomarkers will enhance the investigation of many key issues and questions and will be an important resource in the future.
ChemGlobe: Manganese - Electronic, thermal, and steric data along with an isotope table.
Meta Description: [ The chemical element [Mn] - Manganese - Datasheet ]
It's Elemental: Manganese - Basic physical and historical information.
Meta Description: [ The Element Manganese - Basic Physical and Historical Information ]
Lenntech: Manganese - Physical data, chemical properties, health and environmental effects.
Meta Description: [ Chemical properties, environmental and health effects of manganese ]
500Manganese - Data tables and historic information.
Radiochemistry of Manganese - Full text of the monograph by R. P. Schuman (Dept. of Chemistry, Robert College, Bebek P.K.8, Istanbul, Turkey). [PDF]
Visual Elements: Manganese - General and physical information, source, uses, biological role, key isotopes, and ionisation energies.
404WebElements: Manganese - Extensive information on history, uses, occurrence, compounds, and properties of the element.
Meta Description: [ This WebElements periodic table page contains key information for the element manganese ]
Wikipedia: Manganese - Properties of the element, including its history, applications, and characteristics.
extract Manganese Dioxide. Extract manganese dioxide from alkaline batteries. Use with hydrogen peroxide to create oxygen ...