Peptides (from the Greek πεπτος, "digestible"), are the family of short molecules formed from the linking, in a defined order, of various α-amino acids. The link between one amino acid residue and the next is an amide bond, and is sometimes referred to as a peptide bond.
Proteins are polypeptide molecules. The distinction is that peptides are short and proteins are long. There are several different conventions to determine these, all of which have flaws.
One convention is that those peptide chains that are short enough to be made synthetically from the constituent amino acids are called peptides rather than proteins. However with the advent of better synthetic techniques, peptides as long as hundreds of amino acids can be made, including full proteins like ubiquitin. Native chemical ligation has given access to even longer proteins, and so this convention seems to be outdated.
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EMBL: IEP - Tool for calculating isoelectric point from amino acid sequence, maintained by European Molecular Biology Laboratory, Heidelberg, Germany.
HLA-DR Peptide Binding - Online tool for prediction, for a single letter sequence, including algorithm methodology from UCSF, Fresno, California.
Meta Description: [ HLA-DR Peptide Binding Prediction ]
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ISIS - Databases of BioCatalysis, Protecting Groups, Solid-Phase Synthesis, Chirbase and other chemical data, maintained at Daresbury, Cheshire, England.
Molecular Clocks: Deamidation of Asparaginyl and Glutaminyl Residues in Peptides and Proteins - Review with color illustrations, tables and references to the research literature.
Meta Description: [ Information about the deamidation of asparaginyl and glutaminyl residues in peptides and proteins. ]
PenBase - Curated database devoted to penaeidins, offering comprehensive information about penaeidin properties, function, diversity and nomenclature.
Meta Description: [ PenBase is a curated database devoted to Penaeidins. PenBase provides comprehensive information about penaeidin properties, function, diversity and nomenclature. , Antimicrobial peptides are major components of innate immunity that have been conserved in evolution and found in different phyla of ... ]
Peptaibol - Antibiotic peptide database and tools at Birkbeck College, UL, Bloombury, London.
PeptideMass - Web-based tool for calculating the molecular weight of peptides by sequence, in oxidised, reduced or IAA forms, using its one-letter code, provided by ExPasy, Switzerland.
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Ribosome Elongation Cycle This is a model of the structure of the ribosome during an peptide elongation cycle |