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Cytokines are a group of proteinaceous signalling compounds that like hormones and neurotransmitters are used extensively for inter-cell communication.

While hormones are secreted from specific organs to the blood and neurotransmitters are related to neural acitivity, the cytokines are a more diverse class of compounds in terms of origin and purpose. They are critical to the functioning of both innate and adaptive immune responses. Apart from their importance in the development and functioning of the immune system, cytokines play a major role in a variety of immunological, inflammatory and infectious diseases. They are also involved in several developmental processes during embryogenesis.

Cytokines are produced by a wide variety of cell types (both haemopoietic and non-haemopoietic) and can have effects on both nearby cells or throughout the organism, sometimes strongly dependent on the presence of other chemicals and cytokines. The cytokine family consists mainly of smaller water-soluble proteins and glycoproteins (proteins with an added sugar chain) with a mass of 8-30 kDa.

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RT @WRY999: Children of parents with Alzheimers have elevated blood pressure and elevated blood inflammatory cytokines. http://ow.ly/yM3x
TAWOP (Justin Marley) Tue, 03 Nov 2009 18:30:36 -0000
RT @WRY999: Children of parents with Alzheimers have elevated blood pressure and elevated blood inflammatory cytokines. http://ow.ly/yM3x
Children of parents with Alzheimers have elevated blood pressure and elevated blood inflammatory cytokines. http://ow.ly/yM3x
WRY999 (Bill Yates) Tue, 03 Nov 2009 16:15:45 -0000
Children of parents with Alzheimers have elevated blood pressure and elevated blood inflammatory cytokines. http://ow.ly/yM3x
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Cytokines Online Pathfinder Encyclopedia - COPE, claiming over 10,000 entries, over 19,000 references on cytokine research, extensive hyperlinks, with tables, formulae, graphics, and integrated sub-dictionaries on related disciplines. Includes profile of author Prof. Horst Ibelgaufts.
Meta Description: [ Cytokines Online Pathfinder Encyclopaedia ]

D Systems - Cytokine Facts - Cytokines mini-reviews, their applications, cytokine facts and literature, maintained by RD Systems company.

Molecular Therapy - Collection of academic and professional publications including information on cytokines, cellular and molecular therapy.

2nd International Conference on Cytokine Medicine - Aims to provide a forum for all specialties and disciplines with interests in clinical and scientific aspects of cytokine medicine, including recent advances in cytokine biology, recent data from clinical trials in different diseases, the use of cytokine medicines in healthcare as well as delivery and monitoring cytokine products. The meeting to be held in Manchester, United kingdom on May 19-20, 2005.

Conference on Local Vascular and Inflammatory Mediators - Exploring the future directions in unraveling the roles of local vascular and inflammatory mediators in health and disease and their potential as targets in drug therapy. The meeting to be held in Lund, Sweden on May 26-28, 2005.
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Cytokine - Subscription and submission invitation for articles on study and applications of interleukins, hematopoietic factors, growth factors, cytotoxins, interferons, and putative cytokines in the official journal of the International Cytokine Society, published by Academic Press.

Cytokine - Publishes on the molecular biology, biochemistry, immunology, diagnostic and clinical applications of all known interleukins, hematopoietic factors, growth factors, cytotoxins, interferons, and new cytokines.

Cytokine Family Database - A collection of EST (Expressed Sequence Tag) records of cytokines deposited in the NCBI GenBank.

Cytokine Interest Group - Forum for the interaction of scientists with a common interest in the immunology, molecular biology and physiology of cytokines, information on mini-symposia by NIH-area scientists dealing with multidisciplinary aspects of cytokine research, as well as membership open to all. Maintained by National Institute of Health, Bethesda, Maryland.

Cytokine Reference - A compendium of cytokines and other mediators of host defense. Cytokines structure and function description, gene regulation, in vivo and in vitro activities, diagnostic and therapeutic utilities as well as cytokine classification by family, receptor, name, disease and cell type.

500 Cytokine Signaling Pathway Database - Contains information on signaling pathways of cytokines for biomedical researchers.

Cytokine Webfacts - Subscription only compendium on cytokines and their receptors, consists of the entire content of the Cytokine FactsBook, published by Academic Press, Elsevier Science.

Cytokines - Overview of cytokines, their properties, activities and receptors. Part of immunology course offered by the Department of Veterinary Science and Microbiology at the University of Arizona, USA.

Cytokines and psychiatry - Abstract of review of recent developments in cytokine biology that are relevant to clinical psychiatry. The role of cytokines in various brain activities and pathophysiology of specific psychiatric disorders.
Meta Description: [ Why do cytokines matter? ]

Cytokines at Dalhousie University - Review of main cytokines and their principle activities. Maintained by Faculty of Medicine, Dalhousie University, Canada.
Meta Description: [ The immune system has many different types of cells acting together to take care of unwanted infections and altered cells. Cytokines are the chemicals produced by these cells in order to communicate and orchestrate the attack. ]

500 Cytokines in Allergic Disease - Overview of main cytokines engaged in allergic responses and their therapeutic potential in allergic diseases. Maintained by Medical Education Information Center, University of Texas.

Cytokines Web - Structure and function of cytokines and their receptors, and their potential therapeutic uses, in treatment of cancer and AIDS, provided by the medical university, Beijing, China.
Meta Description: [ Structure and function of cytokines and their receptors. These molecules have many potential theraputic uses, including the treatment of cancer and HIV/AIDS ]

404 Eicosanoids - Arachidonic acid metabolic pathways. Synthesis of prostanoids, lipoxin and leukotriene.

Growth Factors and Cytokines - Introduction to growth factors and cytokines maintained by Michael W. King at the School of Medicine, Indiana State University, Terre Haute, IN.

Hormones and Cytokines - Overview of regulation of the hypothalamic-pituitary-adrenal axis by cytokines: actions and mechanisms of action.

404 ICI Cytokine Data Collection - Information on main cytokines, pictures regarding cytokine receptor classes, links to signal pathways, internet resources, and slide show about signalling pathways inside the cell, maintained by Institute of Clinical Immunology, FSU Jena, Germany.

ImPRINTS - A sub-site of the PRINTS database aimed to help throughout the structural and functional characterization of the immunological molecules including allergens, cytokines, immunoglobulin superfamily, CD and virulence factors.

404 International Cytokine Society - Society affairs, members and application details, conferences, downloadable PDF newsletters, links to journals and other resources. Also discussion group, including archive to 1997, and contact list for postdoctoral posts worldwide.

Molecular Mediators, Cytokines - Eight topic lectures covering cytokines, their first description, features, philosophy, comparison with hormones, chemokines and the classes of receptor families. Part of the pathology course by Alexander G. Izaguirre at University of Medicine and Dentistry of New Jersey.

Muscle and immune proteins - Overview of sarcopenia and potentialities of physical exercise as an prevention method of immunosenescence, correlation between the muscle mass and TNF-alpha:IL-6 ratio.

PRGF. Plasma Rich in Growth Factors - Technique for bone and tissue regeneration, conceived and developed by BTI Biotechnology Institute. Some of his therapeutical applications are oral, maxillofacial, periodontal surgery and dental implants.
Meta Description: [ PRGF, Plasma Rich in Growth Factors, is a breaking-through technique for bone and tissue regeneration, conceived and developed by BTI Biotechnology Institute. Some of his therapeutical applications are oral, maxillofacial, periodontal surgery and dental implants. ]

Research Diagnostics Inc. - Offers, for in vitro research use only, recombinant growth factors, cytokines, chemokines and in some case ELISA kits and receptors, including soluble free fraction VEGF-receptor kit, from Flanders, NJ.
Meta Description: [ Recombinant Human Cytokines and Antibodies from RDI Div of Fitzgerald Industries Intl. ]

SBH Sciences - Promoting collaboration and outsourcing to develop cell culture processes, including proliferation and neutralization bioassays, using their cytokines and growth factors in cell culture media, from manufacturer at Natick, MA.
Meta Description: [ SBH Sciences, is a Biotechnology Company. We are dedicated to the development of cell-based bioassays and efficient cell culture processes for the production of recombinant cytokines and monoclonal antibodies. cell culture, monoclonal antibody, recombinant cytokines., SBH Sciences, is a Biotechno... ]

Structural Biology in the Walter Lab - Studies of the alpha helical cytokine family Interferon-gamma, interferon-alpha, and interleukin-10, their receptors, intracellular signaling molecules with emphasis on understanding the structural basis of molecular recognition events that subsequently lead to cellular signal transduction, maintained by Mark R. Walter laboratory at the University of Alabama at Birmingham.

The International Society for Interferon and Cytokine Research - The cytokine-interferon open forum, downloadable PDF newsletters, links to conferences, meetings, related websites and journals as well as society matters and membership details along with application forms.

Trophic factors - Contains information on neurotrophins, cytokines, growth factors - their main features, receptors and receptor subunits, as well as trophic factor related disorders. Maintained by the Neuromuscular Disease Centre at the Washington University, St.Louis, MO, USA.

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