The history of biology traces man's understanding of the living world from the earliest recorded history to modern times. Though the concept of biology as a single coherent field of knowledge only arose in the 19th century, the biological sciences emerged from traditions of medicine and natural history reaching back to the ancient Greeks (particularly Galen and Aristotle, respectively).

During the Renaissance and Age of Discovery, renewed interest in empiricism as well as the rapidly increasing number of known organisms led to significant developments in biological thought; Vesalius inaugurated the rise of experimentation and careful observation in physiology, and a series of naturalists culminating with Linnaeus and Buffon began to create a conceptual framework for analyzing the diversity of life and the fossil record, as well as the development and behavior of plants and animals. The growing importance of natural theology—partly a response to the rise of mechanical philosophy—was also an important impetus for the growth of natural history (though it also further entrenched the argument from design).

In the 18th century many fields of science—including botany, zoology, and geology—began to professionalize, forming the precursors of scientific disciplines in the modern sense (though the process would not be complete until the late 1800s). Lavoisier and other physical scientists began to connect the animate and inanimate worlds through the techniques and theory of physics and chemistry. Into the 19th century, explorer-naturalists such as Alexander von Humboldt tried to elucidate the interactions between organisms and their environment, and the ways these relationships depend on geography—creating the foundations for biogeography, ecology and ethology. Many naturalists began to reject essentialism and seriously consider the possibilities of extinction and the mutability of species. These developments, as well as the results of new fields such as embryology and paleontology, were synthesized in Darwin's theory of evolution by natural selection. The end of the 19th century saw debates over spontaneous generation and the rise of the germ theory of disease and the fields of cytology, bacteriology and physiological chemistry, though the problem of inheritance was still a mystery.

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PLoS Medicine: New Articles

PLoS Medicine Issue Image | Vol. 6(6) June 2009
Tue, 30 Jun 2009 07:00:00 -0000
Clean water should be recognized as a human right. At the March 2009 United Nations meetings coinciding with the World Water Forum, a declaration that would recognize water as a basic human right was defeated. In this month's Editorial, the PLoS Medicine Editors argue that access to clean water should be declared a basic human right for three reasons. First, access to clean water can substantially reduce the global burden of disease caused by water-borne infections. Second, the privatization of water—as witnessed in Bolivia, Ghana, and other countries—has not effectively served the poor, who suffer the most from lack of access to clean water. Third, the prospect of global water scarcity—exacerbated by climate change, industrial pollution, and population growth—means that no country is immune to a water crisis.Image Credit: Rudhach at flickr.com
Seasonal Hunger: A Neglected Problem with Proven Solutions
Bapu Vaitla et al. Tue, 30 Jun 2009 07:00:00 -0000
Clean Water Should Be Recognized as a Human Right
Tue, 30 Jun 2009 07:00:00 -0000
Can We “Hedge” against the Development of Antiviral Resistance among Pandemic Influenza Viruses?
David K. Shay et al. Tue, 30 Jun 2009 07:00:00 -0000
David K. Shay and Benjamin Ridenhour discuss a modeling study predicting that stockpiling a secondary antiviral for use early in a flu pandemic can forestall resistance to the primary stockpiled drug.
Pralidoxime in Acute Organophosphorus Insecticide Poisoning—A Randomised Controlled Trial
Michael Eddleston et al. Tue, 30 Jun 2009 07:00:00 -0000
In a randomized controlled trial of individuals who had taken organophosphorus insecticides, Michael Eddleston and colleagues find that there is no evidence that the addition of the antidote pralidoxime offers benefit over atropine and supportive care.
What Is the Optimal Therapy for Patients with H5N1 Influenza?
Nicholas J. White et al. Tue, 23 Jun 2009 07:00:00 -0000
Nicholas White discusses optimal dosing of oseltamivir, Robert Webster and Elena Govorkova discuss combination antiviral therapy, and Timothy Uyeki discusses clinical care of patients with H5N1.

EurekAlert! - Biology

Study identifies how tamoxifen stimulates uterine cell growth and cancer
Thu, 02 Jul 2009 00:00:00 -0400
(University of California - San Francisco) University of California - San Francisco researchers have identified a new "feed-forward" pathway linking estrogen receptors in the membrane of the uterus to a process that increases local estrogen levels and promotes cell growth.
'Genetic arms race' between bacteria, viruses subject of stimulus grant
Thu, 02 Jul 2009 00:00:00 -0400
(Michigan State University) The oceans teem with microscopic bacteria that produce much of Earth's oxygen as they absorb carbon dioxide greenhouse gas. But fast-mutating viruses also populate the seas, attacking marine bacteria in an ages-old evolutionary arms race. A Michigan State University researcher will probe that ancient dynamic against the backdrop of environmental and climate change, and the pivotal role played by aquatic bacteria in maintaining the Earth's biological balance.
Learning from locusts
Thu, 02 Jul 2009 00:00:00 -0400
(Queen's University) A similarity in brain disturbance between insects and people suffering from migraines, stroke and epilepsy points the way toward new drug therapies to address these conditions.

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