Mycoplasma is another genus of small microorganisms that resemble bacteria which lack cell walls, but have many differences and are grouped differently.They can be parasitic or saprophytic. Several species are pathogenic in humans, including M. pneumoniae, which is an important cause of pneumonia and other respiratory disorders, and M. genitalium, which is believed to be involved in pelvic inflammatory diseases.They are resistant to antibiotics like penicillin.
Mycoplasma are members of the class Mollicutes. Mollicutes are bacteria which have small genomes, lack a cell wall and have low GC-content (18-40 mol%). There are over 100 recognised species of the genus mycoplasma. Their genome size ranges from 0.6 - 1.35 megabase-pairs. Mycoplasmas are most often parasites or commensals of humans, other animals including insects, and plants. Cholesterol is required for the growth of most of those with animal hosts. Their optimum growth temperature often the temperature of their host if warmbodied (e.g. 37 degrees Celsius in humans) or ambient temperature if the host is unable to regulate its own internal temperature. It is widely believed that Mycoplasmas are descendants of the Lactobacillus-Clostridium branch of the phylogenetic tree (Firmicutes sensu stricto).
Mycoplasma are often found in research laboratories in cell culture often resulting from careless handling; they are relatively difficult to detect and remove from the cell lines and can skew experimental results.
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MypuList - Database on Mycoplasma pulmonis genetics. Provides a complete dataset of DNA and protein sequences linked to the relevant annotations and functional assignments .
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Mycoplasma pulmonis UAB CTIP
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