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Dr. Joshua Lederberg (born May 23, 1925) is an American molecular biologist who is known for his work in genetics, artificial intelligence, and space exploration. He was awarded half of the Nobel Prize in 1958 for his research in genetic structure and function in microorganisms. The other half of that year's prize was shared by Edward Lawrie Tatum and George Wells Beadle.

In addition to his contributions to biology, Lederberg did extensive research in artificial intelligence. This included work in the NASA experimental programs seeking life on Mars and the chemistry expert system Dendral.

Early life and education


Lederberg was born in Montclair, New Jersey and graduated from Stuyvesant High School in New York City at the age of 15. After graduation, he was allowed lab space as part of the American Institute Science Laboratory, a forerunner of the Westinghouse Science Talent Search. He enrolled in Columbia University in 1941, majoring in zoology. Under the mentorship of Francis J. Ryan, he conducted biochemical and genetic studies on the bread mold Neurospora crassa. Intending to receive his MD and fufill his military service obligations, Lederberg worked as a hospital corpsman during 1943 in the clinical pathology laboratory at St. Albans Naval Hospital, where he examined sailors' blood and stool samples for malaria. He went on to receive his undergraduate degree in 1944.

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Joshua Lederberg - Transcript of a 1996 interview conducted by Lev Pevzner. Covers his early life, family and interests, and research.

Joshua Lederberg - Provides a range of information on the collection of papers held at the National Library of Medicine . A major portion of the collection is available in digital format.

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