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Gene therapy is the insertion of genes into an individual's cells and tissues to treat a disease, and hereditary diseases in particular. Gene therapy typically aims to supplement a defective mutant allele with a functional one. Although the technology is still in its infancy, it has been used with some success. Antisense therapy is not strictly a form of gene therapy, but is often lumped together with them.

Background


In the 1980s, advances in molecular biology had already enabled human genes to be sequenced and cloned. Scientists looking for a method of easily producing proteins, such as the protein deficient in diabetics — insulin, investigated introducing human genes to bacterial DNA. The modified bacteria then produce the corresponding protein, which can be harvested and injected in people who cannot produce it naturally.

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Genetic Disorders
Gene Expression :: Biochemistry and Molecular Biology
Biotechnology :: Biology
Genomics :: Genetics

 
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Gene could predict tamoxifen treatment failure http://tinyurl.com/y9n5vz2 Brst cncr therapy reduces mastectomies http://tinyurl.com/y88jqj8
BCSurvivor08 (Tracy Palmer) Tue, 09 Feb 2010 12:43:34 -0000
Gene could predict tamoxifen treatment failure http://tinyurl.com/y9n5vz2 Brst cncr therapy reduces mastectomies http://tinyurl.com/y88jqj8
RT @princessmadiro: mentions Dr. Kaspar's lab MFM&F helps! RT @time Is Gene-Therapy Medical Treatment Ready for Prime Time? - TIME http://bit.ly/4qYtwO
lucyandethel09 (Helen Baldwin) Tue, 09 Feb 2010 10:30:52 -0000
RT @princessmadiro: mentions Dr. Kaspar's lab MFM&F helps! RT @time Is Gene-Therapy Medical Treatment Ready for Prime Time? - TIME http://bit.ly/4qYtwO
A New Tool for Gene Retina Therapy http://ff.im/fDBG8
AjaanRobCMU (AjaanRobCMU) Tue, 09 Feb 2010 08:36:18 -0000
A New Tool for Gene Retina Therapy http://ff.im/fDBG8
mentions Dr. Kaspar's lab MFM&F helps! RT @time Is Gene-Therapy Medical Treatment Ready for Prime Time? - TIME http://bit.ly/4qYtwO
princessmadiro (Miracle For Madison ) Tue, 09 Feb 2010 05:15:56 -0000
mentions Dr. Kaspar's lab MFM&F helps! RT @time Is Gene-Therapy Medical Treatment Ready for Prime Time? - TIME http://bit.ly/4qYtwO
Nanotech gene therapy kills ovarian cancer in mice - Vancouver Sun http://bit.ly/afdeFQ www.bioeden.com
BioEDENUK (BioEDEN UK) Tue, 09 Feb 2010 03:43:59 -0000
Nanotech gene therapy kills ovarian cancer in mice - Vancouver Sun http://bit.ly/afdeFQ www.bioeden.com
RT @ryueyes11: 美 과학자, 3년내 불로장생약 출시 (http://bit.ly/9yZ7U6) "gene therapy 와 stem cell"이 결국 현대판 진시황을 만드는건 아닌지.. 이젠 돈 없으면 죽어야 하는 시대가 올 수도
A_afarensis (루시) Tue, 09 Feb 2010 02:36:37 -0000
RT @ryueyes11: 美 과학자, 3년내 불로장생약 출시 (http://bit.ly/9yZ7U6) "gene therapy 와 stem cell"이 결국 현대판 진시황을 만드는건 아닌지.. 이젠 돈 없으면 죽어야 하는 시대가 올 수도

 
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Gene Therapy - Human Genome Project - Definition, hurdles, ethical issues, and links to more resources on gene therapy provided by the Oak Ridge National Laboratory.
Meta Description: [ An overview of genomics and medicine highlighting the areas of gene testing, genetic counseling, current research, disease-specific information, continuing medical education, publications, and professional societies., Fireworks Splice HTML ]

Gene Therapy Advisory Committee - GTAC - Advises on the ethical acceptability of proposals for gene therapy research on humans taking account of the scientific merits and the potential benefits and risks, and provides advice to UK Health Ministers on developments in gene therapy research.
Meta Description: [ The Gene Therapy Advisory Committee (GTAC)is the UK national research ethics committee for gene therapy clinical research according to the Medicines for Human Use (Clinical Trials) Regulations 2004. It is the only UK ethics committee empowered to approve clinical trials of gene therapy products a... ]

Gene Therapy and Your Child - Development information for the clinical use of gene therapy for children with severe illnesses.
Meta Description: [ Gene therapy carries the excitement of a cure-all for many diseases, the controversy surrounding the altering of human imperfection, and the promise of a medical treatment most of us would never imagine possible. ]

Gene Therapy Clinical Trials Worldwide - Comprehensive source of information on worldwide gene therapy clinical trials compiled by The Journal of Gene Medicine.

Harvard Gene Therapy Initiative - Provides plasmid construction and virus production services for gene therapy in both research and therapeutic applications.
Meta Description: [ Gene Therapy Initiative, Harvard Institute of Human Genetics, Harvard Medical School, Children's Hospital, Boston. Conducts research developing novel gene delivery vector technologies. Research, Vector repository, Ordering info.. ]

Jesse's Journey - The Foundation for Gene and Cell Therapy - A registered charitable organization raising funds for research in gene and cell based therapies focusing on Duchenne muscular dystrophy and other neuromuscular diseases.
Meta Description: [ Duchenne Muscular Dystrophy - Jesse's Journey - The Foundation for Gene and Cell Therapy provides funding for research into Duchenne Muscular Dystrophy. This charitable organization targets neuromuscular diseases like Duchenne MD through research in gene therapy, cell therapy and genetics. ]

Office of Biotechnology Activities at the NIH - Monitors scientific progress and ethical issues in basic and clinical research involving recombinant DNA and human gene transfer at NIH funded institutions.
Meta Description: [ Office of Biotechnology Activities. ]

UK Cystic Fibrosis Gene Therapy Consortium - A consortium whose aims are to provide cystic fibrosis gene therapy updates to researchers, medics, patients and their families.

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