Gourt > Science > Biology > Genetics > Eukaryotic > Animal > Mammal > Human > Databases and Maps > Mutation
In biology, mutations are changes to the genetic material (usually DNA or RNA). Mutations can be caused by copying errors in the genetic material during cell division and by exposure to radiation, chemicals (mutagens), or viruses, or can occur deliberately under cellular control during processes such as meiosis or hypermutation. In multicellular organisms, mutations can be subdivided into germline mutations, which can be passed on to descendants, and somatic mutations. The somatic mutations cannot be transmitted to descendants in animals. Plants sometimes can transmit somatic mutations to their descendants asexually or sexually (in case when flower buds develop in somatically mutated part of plant).
Mutations are considered the driving force of evolution, where less favorable (or deleterious) mutations are removed from the gene pool by natural selection, while more favorable (beneficial or advantageous) ones tend to accumulate. Neutral mutations are defined as mutations whose effects do not influence the fitness of either the species or the individuals who make up the species. These can accumulate over time. The overwhelming majority of mutations have no significant effect, since DNA repair is able to revert most changes before they become permanent mutations, and many organisms have mechanisms for eliminating otherwise permanently mutated somatic cells.
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More on [ Mutation ]
@maro254 Zap, Cosmic Horror, Forcefield, Psychic Membrane, Pulse of the Grid, Force Spike, Abduction, Adv. Hoverguard, __ Mutation
Lespec (Lespec) Tue, 08 Dec 2009 06:01:23 -0000
@maro254 Zap, Cosmic Horror, Forcefield, Psychic Membrane, Pulse of the Grid, Force Spike, Abduction, Adv. Hoverguard, __ Mutation
The New H1N1 Swine Flu Mutation In Ukraine - http://thebirdflupandemic.com/archives/research
wishaponastar (WishUponAStar) Tue, 08 Dec 2009 05:17:16 -0000
The New H1N1 Swine Flu Mutation In Ukraine - http://thebirdflupandemic.com/archives/research
U.S. News & World Report Health Buzz: Gene Mutation Linked to Severe Obesity and Other Health NewsU.... http://reduce.li/mw8sck #severe
blognew (blog new) Tue, 08 Dec 2009 05:15:26 -0000
U.S. News & World Report Health Buzz: Gene Mutation Linked to Severe Obesity and Other Health NewsU.... http://reduce.li/mw8sck #severe
Survival Analysis of Cancer Risk Reduction Strategies for BRCA1/2 Mutation Carriers (Journal of Clin. Onc.) http://short.to/zqvd
libbyshope (Paul Cacciatore) Tue, 08 Dec 2009 05:14:34 -0000
Survival Analysis of Cancer Risk Reduction Strategies for BRCA1/2 Mutation Carriers (Journal of Clin. Onc.) http://short.to/zqvd
@xierakallel oh thats new. ada mutation dah.. emmm .mesti dia gaduh ngan kucing liar somewhere..
shameenmd (Shameen M Dahalan) Tue, 08 Dec 2009 04:26:41 -0000
@xierakallel oh thats new. ada mutation dah.. emmm .mesti dia gaduh ngan kucing liar somewhere..
RT Genetic mutation may link vitamin D to congestive heart failure ... http://brquicken.com
brquicken (Brain Quicken) Tue, 08 Dec 2009 04:23:26 -0000
RT Genetic mutation may link vitamin D to congestive heart failure ... http://brquicken.com
ADAbase: Mutation registry for Adenosine Deaminase Deficiency - Features an introduction, submissions, publications, and an immunodeficiency resource. Includes a gene atlas for the ADA gene.
ADSLdb - Provide up-to-date information about genetic variation of the adenylosuccinate lyase gene. Includes cDNA sequence and gene structure.
Albumin - Contains a list of published albumin mutations with references, accession numbers for nucleotide sequences, the list of registered cases of analbuminemia with references, plus news items of general interest .
Andogen Receptor Gene - A searchable mutations database. Includes a table and map of interacting proteins and links to related resources.
Blood Group Antigen Gene Mutation Database - Deals with mutations in loci of allelic genes that specify the common blood group antigens and the allelic variants of those common genes. Includes an introduction, contributors, and resources.
Meta Description: [ The Blood Group Antigen Gene Mutation Database (BGMUT) - provides information about blood groups, and documents genetic variations or genotypes responsible for various blood group types and systems ]
GeneDis - Features the primary sequences of genes and proteins involved in human genetic diseases. The mutation table shows the location of the mutation on the cDNA, genomic DNA and protein sequence, and the number of exon or intron .
Meta Description: [ The GeneDis Website includes the primary
sequences of genes and proteins involved in human genetic diseases.
Known mutations are incorporated in the gene and protein
sequences using hyperlinks. Other information, such as
biochemical, structural and genomic information, is included as well.
... ]
Institute of Medical Genetics in Cardiff - Database of human gene mutation data . Features publications, newly added genes, and locus specific databases.
MutDB - Public initiative to annotate genomic variants with data that assists in functional annotation. Offers tools to help determine which mutations are the most likely to be the underlying causative agents of disease.
RettBASE : MECP2 - Searchable database of known and novel MECP2 disease-causing mutations and polymorphisms. From the International Rett Syndrome Association.
The p53 Web Site - Features current work, a mutations analysis, and anatomy of the gene . Provided by the Institut Curie .
The Tissue Nonspecific Alkaline Phosphatase Gene Mutations Database - Provide information about genetic variation of the alpl gene responsible for hypophosphatasia. Includes a downloadable list of genotypes and mutations .
X-linked Adrenoleukodystrophy Database - Catalogue and facilitate the analysis of X-ALD mutations and provide background information. Includes the structure of the ABCD1 gene and its gene sequence.
Meta Description: [ This database has been initiated to collect data on mutations found in the gene (ABCD1) responsible for X-linked adrenoleukodystrophy
and provide information on X-ALD. ]
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