PLoS Medicine: New Articles

Ensuring the Involvement of Children in the Evaluation of New Tuberculosis Treatment Regimens
William Burman and colleagues review the barriers to involving children in studies of new tuberculosis treatments and recommend strategies for overcoming these barriers.
Strategies to Reduce Mortality from Bacterial Sepsis in Adults in Developing Countries
Sharon Peacock and colleagues discuss management of adult patients with sepsis in low- and middle-income settings, with a particular emphasis on tropical regions.
Cancer Screening: A Mathematical Model Relating Secreted Blood Biomarker Levels to Tumor Sizes
Sanjiv Gambhir and colleagues describe a linear one-compartment mathematical model that allows estimation of minimal detectable tumor sizes based on blood tumor biomarker assays.
Two Faces of Chondroitin Sulfate Proteoglycan in Spinal Cord Repair: A Role in Microglia/Macrophage Activation
Michal Schwartz and colleagues describe the role of chondroitin sulfate proteoglycan in the repair of injured tissue and in the recovery of motor function during the acute phase after spinal cord injury.

EurekAlert! - Biology

OU researchers isolate microorganisms that convert hydrocarbons to natural gas
Tue, 19 Aug 2008 00:00:00 -0400
(University of Oklahoma) When a group of University of Oklahoma researchers began studying the environmental fate of spilt petroleum, a problem that has plagued the energy industry for decades, they did not expect to eventually isolate a community of microorganisms capable of converting hydrocarbons into natural gas.
Candy-coating keeps proteins sweet
Tue, 19 Aug 2008 00:00:00 -0400
(National Institute of Standards and Technology (NIST)) Researchers at NIST have developed a fast, inexpensive and effective method for evaluating the sugars pharmaceutical companies use to stabilize protein-based drugs for storage at room temperature.
UH researchers win top prize for research with humanitarian applications
Tue, 19 Aug 2008 00:00:00 -0400
(University of Houston) Understanding how microbes govern human and environmental health, two University of Houston researchers -- Yuriy Fofanov and Lennart Johnsson -- understand that what we don't see often carries big-picture implications. They've garnered international recognition for applying such vision while creating technologies to help monitor the sizes and genomic diversity of microbial communities. They were named winners of the second-annual Itanium Solutions Alliance Innovation Contest for the humanitarian applications of their team's research.

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