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In chemistry, a molecule is generally an aggregate of at least two atoms in a definite arrangement held together by special forces. Generally, a molecule is considered the smallest particle of a pure chemical substance that still retains its composition and chemical properties.Molecule Definition Some pure chemical substances existing as liquids or solids (such as metals, molten salts, crystals, etc.), for which such a definition may not always be possible, are best understood as being composed of atoms, not recognizable molecules. In the molecular sciences, a molecule is a sufficiently stable, electrically neutral entity composed of two or more atoms.IUPAC Defintion of Molecule The concept of "monatomic molecule", i.e. a single-atom as found in noble gases, is used almost exclusively in the kinetic theory of gases.* Polyatomic ions may sometimes be usefully thought of as electrically-charged molecules.

History


Although the concept of molecules was first introduced in 1811 by Avogadro, and was accepted by many chemists as a result of Dalton's laws of Definite and Multiple Proportions (1803-1808), with notable exceptions (Boltzmann, Maxwell, Gibbs), the existence of molecules as anything other than convenient mathematical constructs was still an open debate in the physics community until the work of Perrin (1911), and was strenuously resisted by early positivists such as Mach. The modern theory of molecules makes great use of the many numerical techniques offered by computational chemistry. Dozens of molecules have now been identified in interstellar space by microwave spectroscopy.

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