Cell biology (also called cellular biology or cytology, from the Greek kytos, "container") is an academic discipline that studies cells. This includes their physiological properties, their structure, the organelles they contain, interactions with their environment, their life cycle, division and death. This is done both on a microscopic and molecular level. Cell biology research extends to both the great diversity of single-celled organisms like bacteria and the many specialized cells in multicellular organisms like humans.

Knowing the composition of cells and how cells work is fundamental to all of the biological sciences. Appreciating the similarities and differences between cell types is particularly important to the fields of cell and molecular biology. These fundamental similarities and differences provide a unifying theme, allowing the principles learned from studying one cell type to be extrapolated and generalized to other cell types. Research in cell biology is closely related to genetics, biochemistry, molecular biology and developmental biology.

Processes in cell biology

---

Movement of proteins

Every cell typically contains hundreds of different kinds of macromolecules that function together to generate the behavior of the cell. Each type of protein is usually sent to a particular part of the cell. An important part of cell biology is investigation of molecular mechanisms by which proteins are moved to different places inside cells or secreted from cells.

Most proteins are synthesized by ribosomes in the cytoplasm. This process is also known as protein biosynthesis or simply protein translation. Some proteins, such as those to be incorporated in membranes (membrane proteins), are transported into the ER during synthesis and further processed in the Golgi apparatus. From the Golgi, membrane proteins can move to the plasma membrane, to other subcellular comparments or they can be secreted from the cell. The ER and Golgi can be thought of as the "membrane protein synthesis compartment" and the "membrane protein processing compartment", respectively. There is a semi-constant flux of proteins through these compartments. ER and Golgi-resident proteins associate with other proteins but remain in their respective compartments. Other proteins "flow" through the ER and Golgi to the plasma membrane. Motor proteins transport mebrane protein-containing vesicles along cytoskeletal tracks to distant parts of cells such as axon terminals.

More on [ Cell biology ]

CELL-METABOLISM

Heavy Breathing: Energy Conversion by Mitochondrial Respiratory Supercomplexes
Sun, 28 Dec 2008 11:30:06 -0000
Eric A. Schon, Norbert A. Dencher.
Models Use Leptin and Calculus to Count Calories
Sun, 28 Dec 2008 11:30:06 -0000
Kevin D. Hall, Steven B. Heymsfield.
The Liver—A Potential New Player in Islet Regeneration?
Sun, 28 Dec 2008 11:30:06 -0000
Larry G. Moss, Christopher B. Newgard.

Subscribe to Cell_Biology RSS feed